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KMID : 0604020150300020128
Korean Journal of Critical Care Medicine
2015 Volume.30 No. 2 p.128 ~ p.131
A Critical Case of Wernicke¡¯s Encephalopathy Induced by Hyperemesis Gravidarum
Kang Byung-Ju

Kim Min-Gu
Kim Jwa-Hoon
Lee Min-Gee
Jeon Sang-Beom
Kim Ha-Il
Huh Jin-Won
Abstract
Wernicke¡¯s encephalopathy is a reversible but potentially critical disease caused by thiamine deficiency. Most patients complain ofsymptoms such as ophthalmoplegia, ataxia and confusion. Heavy alcohol drinking is commonly associated with the disease, but otherclinical conditions also can provoke it. In pregnant women, hyperemesis gravidarum can lead to the depletion of body thiamine dueto poor oral intake and a high metabolic demand. We report a case of Wernicke¡¯s encephalopathy following hyperemesis gravidarumin a 36-year-old female at 20 weeks of pregnancy, who visited our hospital because of shock with vaginal bleeding. This case suggeststhat although the initial presentation may include atypical symptoms (e.g., shock or bleeding), Wernicke¡¯s encephalopathy should beconsidered, and thiamine replacement should be performed in pregnant women with neurologic symptoms and poor oral intake.
KEYWORD
acute kidney injury, hyperemesis gravidarum, Wernicke encephalopathy
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